白介素18(IL18)單克隆抗體
Monoclonal Antibody to Interleukin 18 (IL18)
IGIF; IL-1g; IL1F4; IL1-F4; Interferon-Gamma-Inducing Factor; Interleukin-1 Family Member 4; Iboctadekin; Interleukin-1 Gamma
- 編號(hào)MAA064Hu28
- 物種Homo sapiens (Human，人)相同的名稱，不同的物種。
- 來(lái)源單抗制備
- 宿主小鼠
- 效價(jià)(克隆號(hào))E2
- Ig亞型 IgG1 Kappa
- 純化方式蛋白A + 蛋白G親和純化
- 標(biāo)記物無(wú)標(biāo)記物
- 免疫原RPA064Hu01-白介素18(IL18)重組蛋白
- 緩沖液成份0.01M 磷酸鹽緩沖液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性狀液體
- 濃度1mg/mL
- 且適物種-
- 應(yīng)用WB; IHC; ICC; IP.
如果抗體需用于流式細(xì)胞術(shù)，請(qǐng)參見(jiàn)流式抗體。 - 下載英文說(shuō)明書(shū) 中文說(shuō)明書(shū)
- 規(guī)格20μl100μl200μl1ml10ml
- 價(jià)格¥ 549¥ 1281¥ 1830¥ 4575¥ 18300
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
Western Blot; Samples: Lane1: Hela cell lysate; Lane2: HepG2 cell lysate;
Primary Ab: 1μg/ml Mouse Anti-Human IL18 Antibody
Second Ab: 0.2μg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
(Catalog: SAA544Mu19)
通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
特異性
該抗體是針對(duì)IL18的小鼠單克隆抗體。在免疫組織化學(xué)染色和免疫印跡實(shí)驗(yàn)中能識(shí)別IL18。
用法
Western blotting: 0.01-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.
儲(chǔ)存
經(jīng)常使用則4°C保存。-20°C保存不超過(guò)兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
贈(zèng)品
增值服務(wù)
抗體標(biāo)記定制服務(wù)
Protein-A/G純化柱
細(xì)胞和組織染色液
抗體陽(yáng)性對(duì)照品
組織/切片定制服務(wù)
磷酸化抗體定制服務(wù)
免疫印跡(WB)實(shí)驗(yàn)服務(wù)
免疫組織化學(xué)(IHC)實(shí)驗(yàn)服務(wù)
免疫細(xì)胞化學(xué)(ICC)實(shí)驗(yàn)服務(wù)
流式細(xì)胞術(shù)(FCM)實(shí)驗(yàn)服務(wù)
免疫沉淀(IP)實(shí)驗(yàn)服務(wù)
免疫熒光(IF)實(shí)驗(yàn)服務(wù)
緩沖液
DAB顯色試劑盒
SABC試劑盒
長(zhǎng)臂生物素標(biāo)記試劑盒
實(shí)時(shí)熒光定量PCR實(shí)驗(yàn)服務(wù)
相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPA064Hu01 | 白介素18(IL18)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA064Hu01 | 白介素18(IL18)活性蛋白 | Cell?culture;?Activity?Assays. |
| RPA064Hu02 | 白介素18(IL18)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPA064Hu61 | 白介素18(IL18)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA064Hu01 | 白介素18(IL18)多克隆抗體 | WB; IHC |
| LAA064Hu71 | 白介素18(IL18)多克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. |
| LAA064Hu81 | 白介素18(IL18)多克隆抗體(異硫氰酸熒光素標(biāo)記) | WB; IHC; ICC; IF. |
| RAA064Hu21 | 白介素18(IL18)重組抗體 | WB; IF; ICC; IHC; IP; FCM. |
| MAA064Hu22 | 白介素18(IL18)單克隆抗體 | WB; IHC |
| MAA064Hu23 | 白介素18(IL18)單克隆抗體 | WB; IHC |
| MAA064Hu25 | 白介素18(IL18)單克隆抗體 | IHC |
| MAA064Hu27 | 白介素18(IL18)單克隆抗體 | WB; IHC; ICC; IP. |
| MAA064Hu21 | 白介素18(IL18)單克隆抗體 | WB; IHC |
| MAA064Hu29 | 白介素18(IL18)單克隆抗體 | WB; IHC; ICC; IP. |
| MAA064Hu24 | 白介素18(IL18)單克隆抗體 | IHC |
| MAA064Hu28 | 白介素18(IL18)單克隆抗體 | WB; IHC; ICC; IP. |
| MAA064Hu26 | 白介素18(IL18)單克隆抗體 | WB; IHC; ICC; IP. |
| FAA064Hu02 | 抗白介素18(IL18)單克隆抗體 | Flow cytometry. |
| FAA064Hu08 | 抗白介素18(IL18)單克隆抗體 | Flow cytometry. |
| FAA064Hu04 | 抗白介素18(IL18)單克隆抗體 | Flow cytometry. |
| FAA064Hu06 | 抗白介素18(IL18)單克隆抗體 | Flow cytometry. |
| SEA064Hu | 白介素18(IL18)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| MEA064Hu | 白介素18(IL18)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法,小樣本) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA064Hu | 白介素18(IL18)檢測(cè)試劑盒(化學(xué)發(fā)光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
| LMA064Hu | 白介素18(IL18)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
| KSA064Hu01 | 白介素18(IL18)檢測(cè)試劑盒DIY材料(酶聯(lián)免疫吸附試驗(yàn)法) | Main materials for "Do It (ELISA Kit) Yourself". |
參考文獻(xiàn)
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| Archives of Virology | Genetic and immunogenicity analysis of porcine circovirus type 2 strains isolated in central China[Pubmed:29305646] |
| Journal of Inflammation | Expression and clinical significance of the NEK7-NLRP3 inflammasome signaling pathway in patients with systemic lupus erythematosus[Pubmed: 30202244] |
| Journal of Affective Disorders | Post-stroke depression and cognitive impairment: study design and preliminary findings in a Brazilian prospective stroke cohort (EMMA study)[Doi: 10.1016/j.jad.2018.10.003] |
| BioScientia Medicina | Sensitivity and Spesificity of Interleukin 18 as Biomarker for Acute Kidney Injury[] |
| International Journal of Molecular Medicine | Ginsenoside Rg1 protects against H2O2?induced neuronal damage due to inhibition of the NLRP1 inflammasome signalling pathway in hippocampal neurons in vitro[Pubmed: 30535505] |
| Nutrients | Effect of Rosmarinic Acid on the Serum Parameters of Glucose and Lipid Metabolism and Oxidative Stress in Estrogen-Deficient Rats[Pubmed: 30691017] |
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| Acta?Histochemica | Pre-administration of luteoline attenuates neonatal sevoflurane-induced neurotoxicity in mice[Doi: 10.1016/j.acthis.2019.04.004] |
| JOURNAL OF DRUG TARGETING | Artemisinin alleviates atherosclerotic lesion by reducing macrophage inflammation via regulation of AMPK/NF-κB/NLRP3 inflammasomes pathway[Pubmed: 31094238] |
| IUBMB Life | Melatonin Enhances Autophagy and Decreases Apoptosis Induced by nanosilica in RAW264. 7 cells[Pubmed: 31018046] |
| American Journal of Reproductive Immunology | Effect of alpha lipoic acid and myoinositol on endometrial inflammasome from recurrent pregnancy loss women[Pubmed: 31148259] |
| INFLAMMATION RESEARCH | TNF-α/calreticulin dual signaling induced NLRP3 inflammasome activation associated with HuR nucleocytoplasmic shuttling in rheumatoid arthritis[Pubmed: 31119302] |
| PLoS One | Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model[Pubmed: 31247004] |
| Journal of Dairy Science | Hepatic nuclear factor kappa B signaling pathway and NLR family pyrin domain containing 3 inflammasome is over-activated in ketotic dairy cows[Pubmed: 31495623] |
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| LIFE SCIENCES | Protective effects of epigallocatechin gallate against ischemia reperfusion injury in rat skeletal muscle via activating Nrf2/HO-1 signaling pathway[Pubmed: 31678278] |
| life sciences | Melatonin biosynthesis restored by CpG oligodeoxynucleotides attenuates allergic airway inflammation via regulating NLRP3 inflammasome[Pubmed: 31738882] |
| International Immunopharmacology | Dexamethasone alleviate allergic airway inflammation in mice by inhibiting the activation of NLRP3 inflammasome[Pubmed: 31780368] |
| Journal of Food Science | Effects of Total Flavonoids from Exocarpium Citri Grandis on Air Pollution Particle‐Induced Pulmonary Inflammation and Oxidative Stress in Mice[Pubmed: 31762039] |
| Antioxidants | Effect of Rosmarinic Acid and Sinapic Acid on Oxidative Stress Parameters in the Cardiac Tissue and Serum of Type 2 Diabetic Female Rats[Pubmed: 31771099] |
| Frontiers in Immunology | The Increase in IL-1β in the Early Stage of Heatstroke Might Be Caused by Splenic Lymphocyte Pyroptosis Induced by mtROS-Mediated Activation of the?…[Pubmed: 31921131] |
| Pharmacological Reports | The dual reno-and neuro-protective effects of dimethyl fumarate against uremic encephalopathy in a renal ischemia/reperfusion model[Pubmed: 32141026] |
| Experimental and Therapeutic Medicine | Induction of autophagy protects human dental pulp cells from lipopolysaccharide?induced pyroptotic cell death[Pubmed: 32104285] |
| Cancer Chemother Pharmacol | Novel complementary antitumour effects of celastrol and metformin by targeting IκBκB, apoptosis and NLRP3 inflammasome activation in diethylnitrosamine-induced …[Pubmed: 31989218] |
| Frontiers in Immunology | TLR2-Melatonin Feedback Loop Regulates the Activation of NLRP3 Inflammasome in Murine Allergic Airway Inflammation[Pubmed: 32117301] |
| molecular immunology | STAT5a induces endotoxin tolerance by alleviating pyroptosis in kupffer cells[Pubmed: 32298872] |
| INVESTIGATIONAL NEW DRUGS | Dual-function chimeric antigen receptor T cells targeting c-Met and PD-1 exhibit potent anti-tumor efficacy in solid tumors[Pubmed: 32772342] |
| Peptides | Liraglutide ameliorates lipotoxicity-induced inflammation through the mTORC1 signalling pathway[Pubmed: 32771373] |
| molecules | Juglone Suppresses LPS-induced Inflammatory Responses and NLRP3 Activation in Macrophages[Pubmed: 32646056] |
| molecular immunology | TLR9 mediates the activation of NLRP3 inflammasome and oxidative stress in murine allergic airway inflammation[Pubmed: 32623292] |
| Inflammopharmacology | Novel complementary coloprotective effects of metformin and MCC950 by modulating HSP90/NLRP3 interaction and inducing autophagy in rats[Pubmed: 32594364] |
| Life Sci | Puerarin ameliorates retinal ganglion cell damage induced by retinal ischemia/reperfusion through inhibiting the activation of TLR4/NLRP3 inflammasome[Pubmed: 32526286] |
| Toxicol Appl Pharmacol | Celastrol augments sensitivity of NLRP3 to CP-456773 by modulating HSP-90 and inducing autophagy in dextran sodium sulphate-induced colitis in rats[Pubmed: 32470352] |
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| Biomedicine & Pharmacotherapy | Cepharanthine attenuates cerebral ischemia/reperfusion injury by reducing NLRP3 inflammasome-induced inflammation and oxidative stress via inhibiting 12?…[Pubmed: 32559840] |
| Molecular Medicine Reports | Effects of PYRIN-containing Apaf1-like protein 1 on isoflurane-induced postoperative cognitive dysfunction in aged rats[Pubmed: 32626997] |
| Food and Agricultural Immunology | Acrylamide induced the activation of NLRP3 inflammasome via ROS-MAPKs pathways in Kupffer cells[] |
| FASEB JOURNAL | Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1‐dependent mitophagy in a Salmonella?…[] |
| Iranian Journal of Allergy, Asthma and Immunology | Increased Level of Caspase-1 in the Serum of Relapsing-remitting Multiple Sclerosis (RRMS) Patients[] |
| Biomarkers of Allergic Asthma and their Association with Serum Parameters[] | |
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| Mol Cell Biochem | Intermittent high glucose induces pyroptosis of rat H9C2 cardiomyocytes via sodium¨Cglucose cotransporter 1[33608832] |
| Life Sci | Inhibition of SGLT1 protects against glycemic variability-induced cardiac damage and pyroptosis of cardiomyocytes in diabetic mice[33508297] |
| Tissue Cell | Protective effects of Oridonin against cerebral ischemia/reperfusion injury by inhibiting the NLRP3 inflammasome activation[33676236] |
| Inflammopharmacology | Dapagliflozin, an SGLT2 inhibitor, ameliorates acetic acid-induced colitis in rats by targeting NF|êB/AMPK/NLRP3 axis[34002329] |
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| LIFE SCIENCES | The NLRP3 inhibitor dapansutrile attenuates folic acid induced nephrotoxicity via inhibiting inflammasome/caspase-1/IL axis and regulating autophagy/proliferation[34560082] |
| Biochim Biophys Acta Mol Cell Biol Lipids | Elaidic acid induced NLRP3 inflammasome activation via ERS-MAPK signaling pathways in Kupffer cells[34610469] |
| Inflammation | Emodin Attenuates LPS-Induced Acute Lung Injury by Inhibiting NLRP3 Inflammasome-Dependent Pyroptosis Signaling Pathway In vitro and In vivo[34787801] |
| J Agric Food Chem | Allicin Ameliorates Intestinal Barrier Damage via Microbiota-Regulated Short-Chain Fatty Acids-TLR4/MyD88/NF-κB Cascade Response in Acrylamide-Induced Rats[34694121] |
| Journal of Inflammation Research | The Supportive Role of NSC328382, a P2X7R Antagonist, in Enhancing the Inhibitory Effect of CRID3 on NLRP3 Inflammasome Activation in Rats with Dextran?…[34321905] |
| Viruses | Interleukin-10-Mediated Lymphopenia Caused by Acute Infection with Foot-and-Mouth Disease Virus in Mice[34960627] |
| Toxicology | Salidroside alleviates liver inflammation in furan-induced mice by regulating oxidative stress and endoplasmic reticulum stress[34450210] |
| Antioxidants | Key Mechanisms and Potential Implications of Hericium erinaceus in NLRP3 Inflammasome Activation by Reactive Oxygen Species during Alzheimer's Disease[34829535] |
| Ecotoxicol Environ Saf | Silica nanoparticles induce pulmonary autophagy dysfunction and epithelial-to-mesenchymal transition via p62/NF-κB signaling pathway[Pubmed:35158278] |
| J Dairy Sci | Overactivation of hepatic mechanistic target of rapamycin kinase complex 1 (mTORC1) is associated with low transcriptional activity of transcription factor EB?…[Pubmed:35248377] |
| Free Radic Biol Med | Silica nanoparticles induce pyroptosis and cardiac hypertrophy via ROS/NLRP3/Caspase-1 pathway[Pubmed:35219847] |
| International Heart Journal | Melatonin Inhibits OGD/R-Induced H9c2 Cardiomyocyte Pyroptosis via Regulation of MT2/miR-155/FOXO3a/ARC Axis[Pubmed:35354753] |
| Journal of Integrative Neuroscience | Gastrodin suppresses pyroptosis and exerts neuroprotective effect in traumatic brain injury model by inhibiting NLRP3 inflammasome signaling pathway[Pubmed:35364660] |
| Perfusion | Insulin reduces pyroptosis-induced inflammation by PDHA1 dephosphorylation-mediated NLRP3 activation during myocardial ischemia-reperfusion injury[Pubmed:35506656] |
| Ecotoxicol Environ Saf | Ambient ozone exposure induces ROS related-mitophagy and pyroptosis via NLRP3 inflammasome activation in rat lung cells[Pubmed:35642860] |
| Medicina | Plasma Concentrations of Cytokines in Patients with Combined Hyperlipidemia and Atherosclerotic Plaque before Treatment Initiation—A Pilot Study[Pubmed:35630041] |
| Pyroptosis Accelerates Spiral Ganglion Neuronal Degeneration Induced by Aminoglycosides in the Cochlea[] | |
| researchsquare | Dexmedetomidine Attenuates Hyperalgesia Induced By Brachial Plexus Root Avulsion By Restoring The GLT-1 Function Via PKA Signaling[] |
| Reseach square | Assessment of selected interleukins (IL-6, IL-17A, IL-18, IL-23) and chemokines (RANTES, IP-10) in children with acute and chronic urticaria[] |
| Anti-inflammatory activity of non-selective PDE inhibitor aminophylline on the lung tissue and respiratory parameters in animal model of ARDS[] |